Andrea Pellagatti Selected Research

Chromosome 5q Deletion Syndrome

7/2015	The molecular pathogenesis of the myelodysplastic syndromes.
1/2015	Recent Advances in the 5q- Syndrome.
1/2013	Activation of the mTOR pathway by the amino acid (L)-leucine in the 5q- syndrome and other ribosomopathies.
1/2012	Haploinsufficiency of ribosomal proteins and p53 activation in anemia: Diamond-Blackfan anemia and the 5q- syndrome.
1/2012	5q- syndrome.
12/2010	Advances in the 5q- syndrome.
12/2009	Clonal heterogeneity in the 5q- syndrome: p53 expressing progenitors prevail during lenalidomide treatment and expand at disease progression.
7/2007	Lenalidomide inhibits the malignant clone and up-regulates the SPARC gene mapping to the commonly deleted region in 5q- syndrome patients.
6/2004	Gene expression profiling in the myelodysplastic syndromes using cDNA microarray technology.

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Andrea Pellagatti Research Topics

Disease

26	Myelodysplastic Syndromes (Myelodysplastic Syndrome) 12/2021 - 06/2004
13	Neoplasms (Cancer) 12/2021 - 07/2011
9	Chromosome 5q Deletion Syndrome 07/2015 - 06/2004
6	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 10/2020 - 12/2009
5	Anemia 07/2015 - 10/2008
3	Leukemia 09/2021 - 01/2017
3	Thrombocytosis (Thrombocythemia) 01/2015 - 12/2010
2	Disease Progression 01/2017 - 12/2009
2	Bone Marrow Failure Disorders 02/2011 - 10/2008
2	Refractory Anemia 04/2008 - 07/2006
1	Spinocerebellar Ataxias (Spinocerebellar Ataxia) 09/2021
1	Mitochondrial Diseases (Mitochondrial Disease) 01/2018
1	Hematologic Neoplasms (Hematological Malignancy) 01/2018
1	Hypoxia (Hypoxemia) 01/2016
1	Genomic Instability 05/2014
1	Renal Cell Carcinoma (Grawitz Tumor) 10/2013
1	Diamond-Blackfan Anemia (Anemia, Diamond Blackfan) 01/2012
1	Autosomal Recessive 3 Severe Congenital Neutropenia 06/2009
1	sideroblastic spinocerebellar ataxia Anemia 04/2008
1	Polycythemia Vera 07/2003

Drug/Important Bio-Agent (IBA)

7	RNA Splicing FactorsIBA 01/2020 - 01/2014
5	Proteins (Proteins, Gene)FDA Link 10/2020 - 07/2007
4	Lenalidomide (CC 5013)FDA Link 01/2017 - 07/2007
3	Biological ProductsIBA 10/2020 - 11/2013
3	Ribosomal Proteins (Ribosomal Protein)IBA 07/2015 - 01/2012
3	MicroRNAs (MicroRNA)IBA 01/2015 - 12/2010
3	Complementary DNA (cDNA)IBA 10/2013 - 07/2003
2	CateninsIBA 12/2021 - 01/2017
2	IronIBA 11/2020 - 04/2008
2	Leucine (L-Leucine)FDA Link 11/2018 - 01/2013
2	Messenger RNA (mRNA)IBA 01/2016 - 10/2013
1	ABT-737IBA 09/2021
1	Protein Kinase CIBA 11/2020
1	Phospholipase C betaIBA 11/2020
1	Cyclin D3IBA 11/2020
1	Protein Isoforms (Isoforms)IBA 01/2019
1	Sirtuin 1IBA 01/2018
1	CytosineIBA 01/2017
1	Azacitidine (5 Azacytidine)FDA Link 01/2017
1	A-Form DNA (A-DNA)IBA 01/2017
1	Transcription Factors (Transcription Factor)IBA 01/2016
1	pimonidazoleIBA 01/2016
1	EnzymesIBA 01/2016
1	Glucose (Dextrose)FDA LinkGeneric 01/2016
1	Oxygen (Dioxygen)IBA 01/2016
1	RNA Precursors (Precursor, mRNA)IBA 01/2016
1	pexmetinibIBA 01/2016
1	p38 Mitogen-Activated Protein KinasesIBA 01/2016
1	Peptides (Polypeptides)IBA 10/2013
1	LigandsIBA 10/2013
1	AdrenomedullinIBA 10/2013
1	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 10/2013
1	Calcitonin Receptor-Like ProteinIBA 10/2013
1	Amino Acids FDA Link 01/2013
1	GTP Phosphohydrolases (GTPases)IBA 07/2011
1	LY-2157299IBA 02/2011
1	Lymphoid Enhancer-Binding Factor 1IBA 06/2009
1	Transforming Growth Factor beta1 (TGF beta 1)IBA 10/2008
1	SD-208IBA 10/2008
1	ATP-Binding Cassette Transporters (ABC Transporters)IBA 04/2008
1	InterferonsIBA 07/2006
1	Heme (Haem)IBA 07/2006

Therapy/Procedure

6	Therapeutics 01/2019 - 12/2010
1	Drug Therapy (Chemotherapy) 01/2016